KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLE2
All Species:
36.06
Human Site:
S101
Identified Species:
52.89
UniProt:
P56282
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56282
NP_002683.2
527
59537
S101
I
P
R
F
V
Y
N
S
E
R
K
K
F
L
P
Chimpanzee
Pan troglodytes
XP_509931
527
59578
S101
I
P
R
F
V
Y
N
S
E
R
K
K
F
L
P
Rhesus Macaque
Macaca mulatta
XP_001095940
525
59213
S104
I
P
R
F
V
Y
N
S
E
R
K
K
F
L
P
Dog
Lupus familis
XP_851216
527
59504
S101
I
P
R
F
V
Y
S
S
E
R
K
K
F
L
P
Cat
Felis silvestris
Mouse
Mus musculus
O54956
527
59368
S101
I
P
R
F
I
Y
N
S
E
R
K
K
F
L
P
Rat
Rattus norvegicus
XP_216727
527
59187
S101
I
P
H
F
I
Y
N
S
E
R
K
K
F
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515002
535
60459
S109
I
P
R
F
V
Y
S
S
E
R
K
K
F
L
P
Chicken
Gallus gallus
Q5ZKQ6
527
59609
P101
I
P
R
Y
I
Y
N
P
D
R
K
R
F
V
P
Frog
Xenopus laevis
NP_001083783
527
59670
S101
I
P
R
Y
V
Y
N
S
E
R
K
K
F
L
P
Zebra Danio
Brachydanio rerio
NP_775353
527
59243
T101
V
P
R
F
I
F
S
T
E
R
K
K
F
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647995
525
58740
R100
A
F
T
V
P
R
F
R
Y
N
Q
R
I
K
K
Honey Bee
Apis mellifera
XP_001120791
454
52119
E53
T
L
K
L
A
I
Q
E
Y
I
R
P
N
T
L
Nematode Worm
Caenorhab. elegans
Q19196
534
60979
D106
Q
P
Y
D
F
D
A
D
L
R
K
M
V
L
R
Sea Urchin
Strong. purpuratus
XP_796825
501
56117
H92
S
N
D
A
P
N
L
H
A
S
A
K
Y
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147081
533
59891
L103
L
R
V
V
D
A
F
L
V
P
R
F
H
Y
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24482
689
78322
G202
N
K
K
Q
N
G
L
G
G
I
A
G
F
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
92.4
93.5
N.A.
90.1
90.8
N.A.
86.1
82.1
81
73.2
N.A.
42.1
39.2
30.8
57.6
Protein Similarity:
100
99.2
94.3
97.1
N.A.
94.8
95.2
N.A.
90.8
91.4
91
88
N.A.
59.7
58
51.1
75.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
93.3
60
93.3
60
N.A.
0
0
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
93.3
100
100
N.A.
13.3
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
36.2
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
56.2
N.A.
N.A.
42.9
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
7
7
0
7
0
13
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
7
7
0
7
7
0
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
0
0
7
57
0
0
0
0
0
0
% E
% Phe:
0
7
0
50
7
7
13
0
0
0
0
7
69
0
0
% F
% Gly:
0
0
0
0
0
7
0
7
7
0
0
7
0
0
0
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
7
0
0
% H
% Ile:
57
0
0
0
25
7
0
0
0
13
0
0
7
0
0
% I
% Lys:
0
7
13
0
0
0
0
0
0
0
69
63
0
13
7
% K
% Leu:
7
7
0
7
0
0
13
7
7
0
0
0
0
63
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
7
0
0
7
7
44
0
0
7
0
0
7
0
0
% N
% Pro:
0
69
0
0
13
0
0
7
0
7
0
7
0
0
69
% P
% Gln:
7
0
0
7
0
0
7
0
0
0
7
0
0
0
0
% Q
% Arg:
0
7
57
0
0
7
0
7
0
69
13
13
0
0
7
% R
% Ser:
7
0
0
0
0
0
19
50
0
7
0
0
0
0
0
% S
% Thr:
7
0
7
0
0
0
0
7
0
0
0
0
0
7
0
% T
% Val:
7
0
7
13
38
0
0
0
7
0
0
0
7
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
0
57
0
0
13
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _